![]() The MEDLINE, Embase and Scopus databases (Januto July 20, 2011) were searched using the following terms: (“quality assurance” OR “quality improvement” OR intervention OR bundle) AND (catheter OR catheterization OR line) AND (infection OR septicaemia OR bacteremia OR sepsis). The review was performed using methodology adapted from the American Heart Association's International Liaison Committee on Resuscitation ( 6). The use of a checklist promotes compliance with best practices during central-line insertion and, thus, may be one of the more important components of the bundle.Īs part of a series of quality improvement initiatives being undertaken by the Canadian Neonatal Network, we performed a systematic review to determine whether the use of bundled interventions that specifically include a checklist to promote compliance with aseptic technique during central-line insertion reduced the incidence of CRBSI in intensive care unit patients. ![]() Bundles have been shown to effectively decrease the incidence of CRBSI ( 4– 5) however, it is not clear which component of the bundle is the most effective. central-line days in infants weighing ≤1000 g ( 1).Ĭampaigns to reduce CRBSI ( 2– 3) have included evidence-based practice ‘bundles’ composed of several interventions including hand hygiene, maximal barrier precautions, chlorhexidine skin antisepsis, optimal site selection and prompt removal of unnecessary central lines. central-line days in infants weighing >2500 g to 9. Recent estimates of CRBSI rates in neonatal intensive care units (NICUs) range from 3. Central venous catheters are essential for providing preterm and critically ill neonates long-term intravenous access for nutritional support and medication administration however, they also place neonates at risk for catheter-related bloodstream infections (CRBSI).
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